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Hypercholesterol


What Is Hypercholesterol?

Cholesterol is a kind of waxy substance (fat-like substance) that’s found in all cells of the body. Cholesterol has very important functions to our body. The body needs cholesterol to develop hormones, vitamin D, and any other substances that useful for foods digesting process.

Basically there are three different types of cholesterol: low density lipoprotein (LDL), high density lipoprotein (HDL), and very low density lipoprotein (VLDL). In addition to three main cholesterol, a kind of lipid that need to be considered is triglycerides. However, triglycerides provide some positive and necessary functions in the body – energy source, insulation and protection, and nutrition.

Then, Hypercholesterol or high cholesterol is a condition when cholesterol level beyond the normal cholesterol levels (more than 240 mg / DL). In the medical world, this condition is also referred to hypercholesterolemia. This condition is a type of abnormal blood lipid profile (dyslipidemia). The state of dyslipidemia is usually marked by the high presence of LDL cholesterol and triglyceride levels and low HDL cholesterol levels.


The Symptoms of High Cholesterol
High cholesterol levels are not necessarily going to show in any indication or any symptom. Symptoms of high cholesterol are usually due to the appearances of heart and vascular diseases or because of the build up of cholesterol deposits in organs. For certain people, the accumulation  of total fat would deposit under the skin and form a xanthoma. When cholesterol layers become thicken the lining of the blood vessels can cause blockages in the heart and brain. If not fatal, this condition will cause chest pain and disruption of blood flow to the brain.

With the increasingly thick layer of cholesterol in blood vessels will cause the blood vessels become stiff and inelastic, causing high blood pressure  symptoms (hypertension). Symptoms of hypertension could be in the forms of headaches or feel heavy at necks. If this situation not handled properly will bring about seriuos impacts, the blocked blood vessels probably would break easily and cause a heart attack or stroke.


High Cholesterol Causes
There are several high cholesterol causes. Some factors can be controlled to prevent from suffering of high cholesterol and remaining causes are difficult to avoid as a result of illnesses. To differentiate the causes of high cholesterol are simply, they can be categorised into two causes:


Primary hypercholesterolemia
High cholesterol often occurs because of some unhealthy living activities. But it is also need to be considered the factors of the family history that brought high cholesterol traits. To sum up, primary Hypercholesterolemia is due to:

- Dietary habits
Unhealthy eating habits by consuming foods that contain high cholesterol or prefering high-fat intake. By consuming foods with high in cholesterol and fat will drive the level of cholesterol in the blood will increase.

- Physical activities
Currently, the available foods in market are often in high contain of calories. If not accompanied by physical inactivities, it will cause calories intake will be dumped into fat. This will lead to increased blood cholesterol levels in the body.

- Obesity
People with overweight or obese have a tendency to have high cholesterol levels. With obesity will also lead to the risk of heart diseases.

- Descendants
High cholesterol levels can rise also due to heredity causes. When the family has a history of high cholesterol, it will increase the likelihood of the offspring receive the same conditions. However, the condition Familial Cholesterol is relatively rare. Patients of Familial Cholesterol will generally have high cholesterol levels even since they were childhood.



Secondary hypercholesterolemia

People with high cholesterol can be caused due to certain illnesses. The disease causes of high cholesterol are: diabetes mellitus, hypothyroidism, nephrotic syndrome, renal failure, liver disease, and Cushing's syndrome. When these diseases are not treated properly it will cause cholesterol levels to rise (hypercholesterolemia). In summary, the relationship between diseases and effects on blood fats is shown in the table below.